DISEASES

Disease-gene associations mined from literature

Literature on ARHGDIG

ARHGDIG [ENSP00000219409]

Rho GDP-dissociation inhibitor 3; Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.

Synonyms:  ARHGDIG,  A2ID99,  C9J3B5,  F1T0H7,  Q99819 ...

Linkouts:  STRING  Pharos  UniProt  OMIM