DISEASES

Disease-gene associations mined from literature

Literature on TBRG1

TBRG1 [ENSP00000409016]

Transforming growth factor beta regulator 1; Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability; Belongs to the TBRG1 family.

Synonyms:  TBRG1,  TBRG1p,  hTBRG1,  E9PI10,  E9PK87 ...

Linkouts:  STRING  Pharos  UniProt  OMIM