DISEASES

Disease-gene associations mined from literature

Literature on GANAB

GANAB [ENSP00000340466]

Neutral alpha-glucosidase AB; Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins . Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia ; Belongs to the glycosyl hydrolase 31 family.

Synonyms:  GANAB,  E9PKU7,  E9PNH1,  E9PQ69,  F5H6X6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM