DISEASES

Disease-gene associations mined from literature

Literature on ATG10

ATG10 [ENSP00000282185]

Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis. ; Belongs to the ATG10 family.

Synonyms:  ATG10,  ATG10p,  hATG10,  A0A024RAK8,  D6RBD1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM