DISEASES

Disease-gene associations mined from literature

Literature on TLE5

TLE5 [ENSP00000221561]

TLE family member 5; Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development. ; Belongs to the WD repeat Groucho/TLE family.

Synonyms:  TLE5,  TLE5p,  hTLE5,  K7ELE3,  K7ELQ8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM