DISEASES

Disease-gene associations mined from literature

Literature on NCEH1

NCEH1 [ENSP00000442464]

Neutral cholesterol ester hydrolase 1; Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration.

Synonyms:  NCEH1,  NCEH1p,  hNCEH1,  A0A0A0MTJ9,  A0A0R4J2G3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM