DISEASES

Disease-gene associations mined from literature

Literature on CBLL1

CBLL1 [ENSP00000401277]

E3 ubiquitin-protein ligase Hakai; E3 ubiquitin-protein ligase that mediates ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1 (By similarity). Targets CDH1 for endocytosis and degradation (By similarity). Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing . Its function in the WMM complex is unknown .

Synonyms:  CBLL1,  CBLL1p,  hCBLL1,  C9J2P9,  C9K074 ...

Linkouts:  STRING  Pharos  UniProt  OMIM