DISEASES

Disease-gene associations mined from literature

Literature on CADPS2

CADPS2 [ENSP00000398481]

Calcium-dependent secretion activator 2; Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity).

Synonyms:  CADPS2,  CADPS2p,  hCADPS2,  A0A087X1P3,  C9IYE1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM