DISEASES

Disease-gene associations mined from literature

Literature on NUDT11

NUDT11 [ENSP00000365160]

Diphosphoinositol polyphosphate phosphohydrolase 3-beta; Cleaves a beta-phosphate from the diphosphate groups in PP- InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5- phosphoribose 1-diphosphate; Belongs to the Nudix hydrolase family. DIPP subfamily.

Synonyms:  NUDT11,  NUDT11p,  hNUDT11,  Q96G61,  Q96G61p ...

Linkouts:  STRING  Pharos  UniProt