Literature on MDM4
MDM4 [ENSP00000356150]
Protein Mdm4; Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions; Belongs to the MDM2/MDM4 family.
Synonyms: MDM4, MDM4p, hMDM4, A0A024R990, A0A087WTR9 ...