Literature on CPLX1
CPLX1 [ENSP00000305613]
Complexin-1; Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles . Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse . Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior. ; Belongs to the complexin/synaphin family.
Synonyms: CPLX1, CPLX1p, hCPLX1, D6RAG3, D6RI11 ...