DISEASES

Disease-gene associations mined from literature

Literature on DNAJB1

DNAJB1 [ENSP00000254322]

DnaJ homolog subfamily B member 1; Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response . Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) .

Synonyms:  DNAJB1,  DNAJB1p,  hDNAJB1,  A0A1B0GX60,  M0QXK0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM