DISEASES

Disease-gene associations mined from literature

Literature on SLC8A2

SLC8A2 [ENSP00000236877]

Sodium/calcium exchanger 2; Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca(2+) and Na(+) excretion. ; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.

Synonyms:  SLC8A2,  SLC8A2p,  hSLC8A2,  F5H6L7,  M0R1Z4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM