DISEASES

Disease-gene associations mined from literature

Literature on H1-3

H1-3 [ENSP00000244534]

Histone H1.3; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).

Synonyms:  H1-3,  HIST1H1D,  P16402,  P16402p,  hP16402 ...

Linkouts:  STRING  Pharos  UniProt  OMIM