DISEASES

Disease-gene associations mined from literature

Literature on KIF20A

KIF20A [ENSP00000378356]

Kinesin-like protein KIF20A; Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end- directed motility.

Synonyms:  KIF20A,  KIF20Ap,  hKIF20A,  D6R9E4,  D6RBN1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM