DISEASES

Disease-gene associations mined from literature

Literature on GKAP1

GKAP1 [ENSP00000365550]

G kinase-anchoring protein 1; Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation.

Synonyms:  GKAP1,  GKAP1p,  hGKAP1,  B4DXS0,  C9J9D2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM