DISEASES

Disease-gene associations mined from literature

Literature on DPH5

DPH5 [ENSP00000359127]

Diphthine methyl ester synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

Synonyms:  DPH5,  DPH5p,  hDPH5,  Q96DC6,  Q9H2P9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM