DISEASES

Disease-gene associations mined from literature

Literature on SLC30A7

SLC30A7 [ENSP00000350278]

Zinc transporter 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity); Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.

Synonyms:  SLC30A7,  SLC30A7p,  hSLC30A7,  H0Y362,  Q8NEW0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM