DISEASES

Disease-gene associations mined from literature

Literature on S1PR5

S1PR5 [ENSP00000328472]

Sphingosine 1-phosphate receptor 5; Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.

Synonyms:  S1PR5,  S1PR5p,  hS1PR5,  A0A087WXR8,  K7EIT5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM