DISEASES

Disease-gene associations mined from literature

Literature on HTR1F

HTR1F [ENSP00000322924]

5-hydroxytryptamine receptor 1F; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Synonyms:  HTR1F,  HTR1Fp,  hHTR1F,  P30939,  P30939p ...

Linkouts:  STRING  Pharos  UniProt  OMIM