DISEASES

Disease-gene associations mined from literature

Literature on DHFR2

DHFR2 [ENSP00000319170]

Dihydrofolate reductase 2, mitochondrial; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR.

Synonyms:  DHFR2,  DHFR2p,  hDHFR2,  C9JJ68,  Q86XF0 ...

Linkouts:  STRING  Pharos  UniProt