Literature on SIDT2
SIDT2 [ENSP00000314023]
SID1 transmembrane family member 2; Mediates the translocation of RNA and DNA across the lysosomal membrane during RNA and DNA autophagy (RDA), a process in which RNA or DNA is directly imported into lysosomes in an ATP- dependent manner, and degraded . Involved in the uptake of single-stranded oligonucleotides by living cells, a process called gymnosis . Involved in the uptake of single-stranded oligonucleotides by living cells, a process called gymnosis. In vitro, mediates the uptake of linear DNA more efficiently than that of circular DNA, but exhibits similar uptake efficacy toward RNA and DNA. Binds long double-stranded RNA (dsRNA) (500 - 700 base pairs), but not dsRNA shorter than 100 bp (By similarity). ECO:0000269|PubMed:27046251, ECO:0000269|PubMed:27846365,
Synonyms: SIDT2, SIDT2p, hSIDT2, C9JBG5, E9PMC3 ...