DISEASES

Disease-gene associations mined from literature

Literature on FUT3

FUT3 [ENSP00000305603]

Galactoside 3(4)-L-fucosyltransferase; May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. May be involved in blood group Lewis determination; Lewis-positive (Le(+)) individuals have an active enzyme while Lewis-negative (Le(-)) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L- fucosyl links.

Synonyms:  FUT3,  FUT3p,  hFUT3,  K7ENT3,  K7EQ20 ...

Linkouts:  STRING  Pharos  UniProt  OMIM