DISEASES

Disease-gene associations mined from literature

Literature on C1QL3

C1QL3 [ENSP00000298943]

Complement C1q-like protein 3; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production (By similarity).

Synonyms:  C1QL3,  C1QL3p,  hC1QL3,  A0A3B0J0F3,  ADIJ ...

Linkouts:  STRING  Pharos  UniProt