DISEASES

Disease-gene associations mined from literature

Literature on ENPP6

ENPP6 [ENSP00000296741]

Glycerophosphocholine cholinephosphodiesterase ENPP6; Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells . Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet- activating factor (PAF) and lysoPAF, but not other lysophospholipids (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

Synonyms:  ENPP6,  ENPP6p,  hENPP6,  D6R9P1,  Q6UWR7 ...

Linkouts:  STRING  Pharos  UniProt