DISEASES

Disease-gene associations mined from literature

Literature on ZNF462

ZNF462 [ENSP00000277225]

Zinc finger protein 462; Zinc finger nuclear factor involved in transcription by regulating chromatin structure and organization (PubMed:20219459, PubMed:21570965). Involved in the pluripotency and differentiation of embryonic stem cells by regulating SOX2, POU5F1/OCT4, and NANOG . By binding PBX1, prevents the heterodimerization of PBX1 and HOXA9 and their binding to DNA (By similarity). Regulates neuronal development and neural cell differentiation .

Synonyms:  ZNF462,  ZNF462p,  hZNF462,  H0Y6H9,  H3BLX4 ...

Linkouts:  STRING  Pharos  UniProt