Literature on UHRF2
UHRF2 [ENSP00000276893]
E3 ubiquitin-protein ligase UHRF2; E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. E3 SUMO-, but not ubiquitin-, protein ligase for ZNF131. ECO:0000269|PubMed:15178429, ECO:0000269|PubMed:15361834,
Synonyms: UHRF2, UHRF2p, hUHRF2, A0A0A0MSQ3, B1AL33 ...