DISEASES

Disease-gene associations mined from literature

Literature on TMEM175

TMEM175 [ENSP00000264771]

Endosomal/lysosomal potassium channel TMEM175; Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. Constitutes the major lysosomal potassium channel.

Synonyms:  TMEM175,  TMEM175p,  hTMEM175,  D3DVN5,  D6RAJ5 ...

Linkouts:  STRING  Pharos  UniProt