DISEASES

Disease-gene associations mined from literature

Literature on HCN4

HCN4 [ENSP00000261917]

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih). May mediate responses to sour stimuli. ECO:0000269|PubMed:10430953, ECO:0000269|PubMed:16407510,

Synonyms:  HCN4,  HCN4p,  hHCN4,  Q9Y3Q4,  Q9Y3Q4p ...

Linkouts:  STRING  Pharos  UniProt  OMIM