DISEASES

Disease-gene associations mined from literature

Literature on REV1

REV1 [ENSP00000258428]

DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. ECO:0000269|PubMed:11278384, ECO:0000269|PubMed:11485998,

Synonyms:  REV1,  REV1p,  hREV1,  C9JPS2,  F8WCR0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM