DISEASES

Disease-gene associations mined from literature

Literature on DHX29

DHX29 [ENSP00000251636]

ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity. Rule:MF_03068, ECO:0000269|PubMed:19109895,; Belongs to the DEAD box helicase family. DEAH subfamily.

Synonyms:  DHX29,  DHX29p,  hDHX29,  A0A087WYN9,  H0Y8L1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM