DISEASES

Disease-gene associations mined from literature

Literature on H1-1

H1-1 [ENSP00000244573]

Histone H1.1; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).

Synonyms:  H1-1,  HIST1H1A,  Q02539,  Q02539p,  hQ02539 ...

Linkouts:  STRING  Pharos  UniProt  OMIM