Literature on OTUD5
OTUD5 [ENSP00000156084]
OTU domain-containing protein 5; Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro).
Synonyms: OTUD5, OTUD5p, hOTUD5, A0A024QZ09, A0A087WXV6 ...