DISEASES

Disease-gene associations mined from literature

Literature on SPINDOC

SPINDOC [ENSP00000294244]

Spindlin interactor and repressor of chromatin-binding protein; Negatively regulates the transcriptional activator activity of SPIN1 via inhibition of its histone methyl-binding ability. Represses the expression of a number of SPIN1-regulated genes and the SPIN1-mediated activation of the Wnt signaling pathway. Can also inhibit the histone methyl-binding abilities of SPIN2A, SPIN2B, SPIN3 and SPIN4 .

Synonyms:  SPINDOC,  H0YGK9,  H0YGY5,  Q9BUA3,  H0YGK9p ...

Linkouts:  STRING  Pharos  UniProt