DISEASES

Disease-gene associations mined from literature

Literature on ROBO3

ROBO3 [ENSP00000380903]

Roundabout homolog 3; Thought to be involved during neural development in axonal navigation at the ventral midline of the neural tube (By similarity). In spinal chord development plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1 (By similarity). Required for hindbrain axon midline crossing . ; Belongs to the immunoglobulin superfamily. ROBO family.

Synonyms:  ROBO3,  ROBO3p,  hROBO3,  F5GWJ5,  F5H0K7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM