DISEASES

Disease-gene associations mined from literature

Literature on TMEM170B

TMEM170B [ENSP00000368737]

Transmembrane protein 170B; Negatively regulates the canonical Wnt signaling in breast cancer cells. Exerts an inhibitory effect on breast cancer growth by inhibiting CTNNB1 stabilization and nucleus translocation, which reduces the activity of Wnt targets . ; Belongs to the TMEM170 family.

Synonyms:  TMEM170B,  Q5T4T1,  Q5T4T1p,  hQ5T4T1,  100113407 ...

Linkouts:  STRING  Pharos  UniProt