DISEASES

Disease-gene associations mined from literature

Literature on SPDEF

SPDEF [ENSP00000363149]

SAM pointed domain-containing Ets transcription factor; May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter.

Synonyms:  SPDEF,  O95238,  O95238p,  hO95238,  1YO5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM