DISEASES

Disease-gene associations mined from literature

Literature on SIK2

SIK2 [ENSP00000305976]

Serine/threonine-protein kinase SIK2; Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

Synonyms:  SIK2,  SIK2p,  hSIK2,  A0A024R3G7,  Q9H0K1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM