DISEASES

Disease-gene associations mined from literature

Literature on RETSAT

RETSAT [ENSP00000295802]

All-trans-retinol 13,14-reductase; Catalyzes the saturation of all-trans-retinol to all-trans- 13,14-dihydroretinol. Does not exhibit any activity toward all-trans- retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers. May play a role in the metabolism of vitamin A. Independently of retinol conversion, may regulate liver metabolism upstream of MLXIPL/ChREBP. May play a role in adipocyte differentiation. ; Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily.

Synonyms:  RETSAT,  H0YGU3,  H7BZ16,  H7BZ81,  H7C3J0 ...

Linkouts:  STRING  Pharos  UniProt