DISEASES

Disease-gene associations mined from literature

Literature on DIO1

DIO1 [ENSP00000354643]

Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.

Synonyms:  DIO1,  DIO1p,  hDIO1,  A0A087WVX4,  A0A087WYB0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM