DISEASES

Disease-gene associations mined from literature

Literature on GCNT3

GCNT3 [ENSP00000379377]

Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I- branching enzyme activity by converting linear into branched poly-N- acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.

Synonyms:  GCNT3,  GCNT3p,  hGCNT3,  A0A024R5T9,  H0YM40 ...

Linkouts:  STRING  Pharos  UniProt  OMIM