DISEASES

Disease-gene associations mined from literature

Literature on LYVE1

LYVE1 [ENSP00000256178]

Lymphatic vessel endothelial hyaluronic acid receptor 1; Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Synonyms:  LYVE1,  LYVE1p,  hLYVE1,  B2R672,  E7EPC7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM