DISEASES

Disease-gene associations mined from literature

Literature on NUTF2

NUTF2 [ENSP00000219169]

Nuclear transport factor 2; Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import.

Synonyms:  NUTF2,  NUTF2p,  hNUTF2,  A0A024R6Y2,  H3BRV9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM