DISEASES

Disease-gene associations mined from literature

Literature on SVIL

SVIL [ENSP00000348128]

Supervillin; [Isoform 1]: Forms a high-affinity link between the actin cytoskeleton and the membrane. Is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation . Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function .

Synonyms:  SVIL,  A0A0J9YWY6,  O95425,  O95425p,  hO95425 ...

Linkouts:  STRING  Pharos  UniProt  OMIM