DISEASES

Disease-gene associations mined from literature

Literature on IBTK

IBTK [ENSP00000305721]

Inhibitor of Bruton tyrosine kinase; Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. Down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription.

Synonyms:  IBTK,  D6R9F4,  E7EPI0,  E9PDR5,  H0Y9N7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM