DISEASES

Disease-gene associations mined from literature

Literature on MMS22L

MMS22L [ENSP00000275053]

Protein MMS22-like; Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double- strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA.

Synonyms:  MMS22L,  MMS22Lp,  hMMS22L,  E2QRD4,  H0Y8J1 ...

Linkouts:  STRING  Pharos  UniProt