DISEASES

Disease-gene associations mined from literature

Literature on MOSMO

MOSMO [ENSP00000454926]

Modulator of smoothened protein; Acts as a negative regulator of hedgehog signaling probably by promoting internalization and subsequent degradation of smoothened protein (SMO) present in the ciliary membrane. Plays a role in sonic hedgehog (SHH)-induced spinal neural progenitor cells differentiation.

Synonyms:  MOSMO,  A0A075B731,  H3BP60,  H3BQB3,  H3BS23 ...

Linkouts:  STRING  Pharos  UniProt