DISEASES

Disease-gene associations mined from literature

Literature on DNTTIP1

DNTTIP1 [ENSP00000361705]

Deoxynucleotidyltransferase terminal-interacting protein 1; Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro) . Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.

Synonyms:  DNTTIP1,  DNTTIP1p,  hDNTTIP1,  F2Z2A4,  H0Y501 ...

Linkouts:  STRING  Pharos  UniProt  OMIM