DISEASES

Disease-gene associations mined from literature

Literature on RNF13

RNF13 [ENSP00000341361]

E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA .

Synonyms:  RNF13,  RNF13p,  hRNF13,  C9IY58,  C9J383 ...

Linkouts:  STRING  Pharos  UniProt  OMIM