Literature on CMTM4
CMTM4 [ENSP00000333833]
CKLF-like MARVEL transmembrane domain-containing protein 4; Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. May protect PD- L1/CD274 from being polyubiquitinated and targeted for degradation. ; Belongs to the chemokine-like factor family.
Synonyms: CMTM4, CMTM4p, hCMTM4, J3QRP2, Q8IZR5 ...